Abstract: CONCLUSIONS: The most common gp46 mutations were not associated clinical status because they were found in only one individual, except for the V247I mutation, that was found at viral clones from HAM/TSP ad HC individuals.

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Abstract: The remaining frequent mutation (V247I) was present in both groups (p = 0.0014).

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Result: Among these common mutations, one (S35L) was exclusive to the HC group, three (F14S, N42H, G72S) were exclusive to the HAM/TSP group and, finally, one mutation (V247I) was found in both groups but with

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