Stability of the HTLV-1 glycoprotein 46 (gp46) gene in an endemic region of the Brazilian Amazon and the presence of a significant mutation (N93D) in symptomatic patients.
Result: Six of the 40 samples analyzed in the present study were diagnosed with HAM/TSP, of which, two presented amino acid mutations (one patient with S72G and the other with both L70I and S103P).
Table: L70I
Discussion: Two of the six patients with HAM/TSP presented amino acid mutations, one with S72G and the other with L70I and S103P.
HTLV1 mutation literature information.
PMID: 
2018
Virology journal
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