Analyses of HTLV-1 sequences suggest interaction between ORF-I mutations and HAM/TSP outcome.
PMID: 27553711
2016
Infection, genetics and evolution
Introduction: demonstrated two natural allelic variants of p12: a lysine-to-arginine change at position 88, which was found more frequently in patients with HAM/TSP and could be important for HTLV-1 outcome.