Analyses of HTLV-1 sequences suggest interaction between ORF-I mutations and HAM/TSP outcome.
PMID: 27553711
2016
Infection, genetics and evolution
Method: We selected the most frequent natural mutations within ORF-I sequences (F3L, S23P, D26N, G29S, P34L, C39R, L40F, P45L, F61L, S63P, L66P, S69G, R83C, R88K and P91S) to evaluate their possible association with the development of HAM/TSP using the Excel program.
Result: First, Bayesian network analysis with all sequences showed a central association
HTLV1 mutation literature information.
PMID: 
2016
Infection, genetics and evolution
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