Result: Of 24 subjects, the TRE-1 G232A mutation was detected in 16 (66.7%) and the TRE-2 A184G mutation in 13 (54.2%).
Result: The frequency of the substitution A G in the second nucleotide (A domain) of the TRE-1 motif (the TRE-1 G232A mutation) and the substitution G A in the third nucleotide (A domain) of the TRE-2 motif (the TRE-2 A184G mutation) was summarized in Table 1.
Result: Thus, all the 13 subjects with the TRE-2 A184G mutation had the TRE-1 G232A mutation together.
Result: We also found that the frequency of double mutations of the TRE-1 G232A and the TRE-2 A184G in HIV/HTLV-1-coinfected was high (54.2%).
Correlation between LTR point mutations and proviral load levels among human T cell lymphotropic virus type 1 (HTLV-1) asymptomatic carriers.
Result: Again, a significant difference in detection of the A184G mutation was evident between subjects with high and low PvLs and betweeen those with high and intermediate PvLs (p < 0.05 both), but not between the low and intermediate PvL groups (p > 0.05).
Result: These analyses revealed two relevant G232A mutation within the TRE-1 region and an A184G mutation within the TRE-2 region numbered according to the transcription start sit
Result: there was no similar association among those who were HTLV-1 positive with the A184G mutation (Figure 2).
Discussion: Therefore, additional experimental supports are needed to rule out the potential importance of the A184G mutations and functional connection between A184G and G232A mutations.
HTLV1 mutation literature information.
PMID: 
2012
Virology journal
Browser Board
Co-occurred Entities
Filtrator
ViMRT