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 HPV mutation literature information.


  Worldwide genetic variations in high-risk human papillomaviruses capsid L1 gene and their impact on vaccine efficiency.
 PMID: 33636291       2021       Gene
Abstract: Four mutations were frequently observed in HPV16 L1 sequences: T353P in the HI loop, H228D in the EF loop, T266A in the FG loop, and T292A in the FG loop.


  Characterization of major capsid protein (L1) variants of Human papillomavirus type 16 by cervical neoplastic status in Indian women: Phylogenetic and functional analysis.
 PMID: 31944308       2020       Journal of medical virology
Abstract: The substitutions N181T, T353P, and T389S were significantly associated with high-grade cervical disease.


  HPV16 L1 diversity and its potential impact on the vaccination-induced immunity.
 PMID: 32304786       2020       Gene
Abstract: Overall, 4 mutations were frequently found in HPV16 sequences: T176N and N181T in EF loop; A266T in the FG loop and T353P/I/N HI loop.



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