Introduction: reported that the
A1668G,
G2073A,
T2169C,
T2189C,
A2453T,
C2454T,
A2587T and
G2650A mutations of HPV16
E1 were identified only in
high-grade dysplasia cases in a Greek population, and this result indicated that those mutations may play an important role in
cervical carcinogenesis.