HPV mutation literature information.


  Human papillomavirus type 16 variant analysis of E6, E7, and L1 [corrected] genes and long control region in [corrected] cervical carcinomas in patients in northeast China.
 PMID: 21593270       2011       Journal of clinical microbiology
Abstract: The most frequently observed variation sites were T178G (32.69%) in E6; A647G (34.62%), G666A (38.46%), and T846C (32.69%) in E7; C6826T (36.17%) and G7060A (61.70%) in L1; and G7521A (98.08%) in the LCR.


  [Human papillomavirus type 16 variant analysis of upstream regulatory region and E6, E7 oncogene from cervical cancer patients in Beijing].
 PMID: 20423887       2010       Yi chuan
Abstract: A total of 8 hot mutation spot was identi-fied, which were URR G7521A (100%), C7435G (96.77%), C24T (45.16%), A7729C (45.16%), G7839A (45.16%), E6 T178G (41.94%), E7 A647G (45.16%), and T846C (45.16%).
Abstract: Our results suggested that the mutations of G7521A, A7729C, G7839A, T178G, T350G, A647G, and G658A were likely to be a


  [Gene characterization of E6 and E7 gene of human papillomavirus of 15 cervical cancer in Beijing].
 PMID: 20104743       2009       Zhonghua shi yan he lin chuang bing du xue za zhi
Abstract: There were two nucleotide mutation at E6 position 178 (T-->G,D25E) and at E7 position 647 (A-->G, N29S) in 4 Asian type like viruses.


  Co-mutation of HPV16 E6 and E7 genes in Thai squamous cervical carcinomas.
 PMID: 12820481       2003       Anticancer research
Abstract: A mutation from T to G at nucleotide 178, leading to a change from aspartate to glutamate (D25E), was the most common variation accounting for 70%.



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