Abstract: Among the high-level variations found in
ICC, six were located in the
E1/
E2 genes, and all of them were non-synonymous substitutions (
Q142K,
M207I, and
L262V for
E1;
D153Y,
R302T, and
T357A for
E2).
Result: Among the
E1 variants tested,
M207I had a significantly reduced ability to support replication of the origin plasmid relative to the prototype
E1, whereas
Q142K and
L262V yielded similar levels of repl
HPV mutation literature information.
PMID: 
2020
Frontiers in microbiology
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