Abstract: Although this study has some limitations such as a small sample size and not enough clinical data, these finding suggests that the distinctive distribution of HPV 16 As-variant E6 D25E and E7 N29S might be associated with geographical dependence rather than disease progression.
Abstract: At the amino acid level, the isolates showed 14 variants including E6 Q14H, E6 D25E, E6 I27R, E6 H78Y, E6 L83V, and E7
Analysis of mutations in the E6/E7 oncogenes and L1 gene of human papillomavirus 16 cervical cancer isolates from China.
PMID: 16603519
2006
The Journal of general virology
Abstract: The results also showed that the prevalences of three hot spots of E7 nucleotide variation, N29S, S63F and a silent variation, nt T846C, were 70.2 % (33/47), 51.1 % (24/47) and 61.7 % (29/47), respectively.
Co-mutation of HPV16 E6 and E7 genes in Thai squamous cervical carcinomas.
Abstract: Interestingly, 90% of these E6 (D25E) variants coincided with a specific type of E7 mutation, N29S.
Abstract: This is the first finding of coordinated change between E6 (D25E) and E7 (N29S) in HPV, which might indicate a specific variant for the Thai population.
Human papillomavirus type 16 intratypic variant infection and risk for cervical neoplasia in southern China.
PMID: 12195358
2002
The Journal of infectious diseases
Abstract: The E7 N29S substitution, reported to have a higher risk in Korean women, was found equally distributed among normal and various degrees of neoplasia.
HPV mutation literature information.
PMID: 
2007
Journal of medical virology
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