Genetic variability of the HPV16 early genes and LCR. Present and future perspectives.
PMID: 34847982
2021
Expert reviews in molecular medicine
Abstract: Nowadays, specific mutations of HPV16 DNA have been associated with an increased risk of high-grade squamous intraepithelial lesions and invasive cervical cancer (ICC) development, including E6: Q14H, H78Y, L83V, Epsilon7: N29S, S63F, E2: H35Q, P219S, T310K, E5: I65V, whereas highly conserved regions of viral DNA have been extensively characterised.
HPV mutation literature information.
PMID: 
2021
Expert reviews in molecular medicine
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