literature

Genetic variability and functional implication of the long control region in HPV-16 variants in Southwest China.

PMID: 28767682 2017 PloS one

Result: The other common LCR changes were A7730C, A7175C, T7177C, T7201C, C7270T, G7842A, C24T, A7287C and A7289C with mutation frequencies of approximately 71% (34/48), 65% (31/48), 65% (31/48), 65% (31/48), 65% (31/48), 65% (31/48), 65% (31/48), 63% (30/48) and 46% (22/48), respectively.

Result: When compared with the asymptomatic carriers, A7175C, T7177C, T7201C, C7270T, A7287C, A7289C,

PMID: 27546189 2016 APMIS

Abstract: The most commonly observed LCR variations were 7521G>A (91.5%), 7730A>C (59.6%), and 7842G>A (59.6%).

Intratypic variants of human papillomavirus type 16 and risk of cervical neoplasia in Taiwan.

PMID: 23852681 2013 Journal of medical virology

Abstract: Similar significant associations with cervical intraepithelial neoplasia grade 3 or worse were also observed for distinct nucleotide substitutions, including T178A/G, A647G, A7730C/G, T7781C, G7842A, and C24T/G.

Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, China.

PMID: 24099556 2013 BMC cancer

Result: Several variations in E6 and LCR were co-segregated, including T178G in E6 gene and T7201C, C7270T, A7287C, A7289C, A7730C, G7842A in LCR, which were observed in 106 isolates (34.9%, 106/304).

Table: G7842A

Sequence variation and the transcriptional activity of the upstream regulatory region in human papillomavirus 16 E7 variants in cervical cancer of Korean women.

PMID: 16012730 2005 Oncology reports

Abstract: The other sequence variations, which were matched with the TFBS, were A7485C, G7489A, T7743G and G7842A.

Human papillomavirus type-16 variants in Quechua aboriginals from Argentina.

PMID: 12601763 2003 Journal of medical virology

Abstract: We identified a new variant, the Argentine Quechua-51 (AQ-51), similar to B-14 plus two additional changes: G7842-->A and A7837-->C; phylogenetic inference allocated it in the Asian-American branch.