Abstract: G7193T and G7521A variants, accounting for 100% of the infections, were predicted to locate at the binding site for FOXA1 and SOX9,
Conclusion: G7193T and G7521A detected in all the infections, were predicted to locate at the binding site for FOXA1 and SOX9, respectively.
Result: G7193T and G7521A variants, which accounted for 100% of the infections, were located at the binding site for Forkhead box protein A1 (FOXA1) and sex-determining region Y-box 9 (SOX9), respectively.
Result: The mutation frequency varied from 2% (1/48) to 100% (48/48), among which the G7193T and G7521A variants got a mutation frequency of 100%.
Table: G7193T
Human papillomavirus type 16 long control region and E6 variants stratified by cervical disease stage.
PMID: 24823962
2014
Infection, genetics and evolution
Result: Result: G7193T was found in 61% (95%CI 42-77%) of control sequences and 66% (55-77%) of cases giving a crude OR of 1.28 (0.50-3.20; p = 0.665).
Result: In addition, variants bearing both G7193T and G7520A substitutions did not alter the ability of p97 to drive luciferase reporter expression in one study.
Result: Of the five LCR variant positions, G7193T and G7520A were present in around 65% and 69% of sequences, respectively, while A7316C, T7449C and T7495C were present in around 10-15% of sequences, mostly in combination with other LCR or E6 variant sites.
Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, China.
Abstract: The most commonly observed LCR variations were the transition replacement G7193T, 7434CIns, G7521A and 7863ADel (100%).
Result: The most common LCR variations were G7193T, 7434CIns, G7521A, 7863ADel, which were found in 100% of HPV16 isolates.
Result: The variation o
Discussion: Because of the strong cosegregation of the co-variations of G7193T, 7434CIns, C7436T, G7521A, and 7863Adel, it is impossible to determine if each variation in it was individually responsible for risk for developing CIN2,3.
Sequence variation and the transcriptional activity of the upstream regulatory region in human papillomavirus 16 E7 variants in cervical cancer of Korean women.
Abstract: The sequence variations T7781C and C7786T were matched with YY1 binding sites, G7193T and C7689A were matched with TEF1 binding sites, and C7394T and C7395T were matched with GRE binding sites.
HPV mutation literature information.
PMID: 
2017
PloS one
Browser Board
Co-occurred Entities
Filtrator
ViMRT