Association of Human Papillomavirus Type 16 Long Control Region Variations with Cervical Cancer in a Han Chinese Population.
PMID: 32308546
2020
International journal of medical sciences
Abstract: For the sub-lineage analysis, only C7873G variations were significantly different between the case and control groups in the A4 (As) variant (P=0.039).
Result: The C7873G variation was significantly different between the case (8.3%) and control (18.4%) group (P=0.039), and the A7232C showed a trend to associate with cervical cancer (case: 0% vs control: 3.9%; P=0.068) in the HPV16 A4 (As) variant.
Discussion: In the current study, our results also showed that the distribution of C7873G was significantly different
Discussion: found that G7428A and C7873G in the A4 (As) variant, which are proximal to the p97 promoter, showed higher transcriptional activity than other A4 (As) and A1-A3 (EUR) variants.
HPV mutation literature information.
PMID: 
2020
International journal of medical sciences
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