literature

HPV mutation literature information.

Genetic variations in E6, E7 and the long control region of human papillomavirus type 16 among patients with cervical lesions in Xinjiang, China.

PMID: 30930693 2019 Cancer cell international

Result: The remaining 29 mutations were mainly T7447C (39/95, 40.1%), followed by T7199C (16/95, 16.8%), C7268T (16/95, 16.8%), A7285C (16/95, 16.8%), T7711G (16/95, 16.8%), A7727C (16/95, 16.8%), G7839A (16/95, 16.8%) and C24T (16/95, 16.8%).

Result: We also found that six loci, T7199C, C7268T, A7285C, A7727C, G7839A, and C24T, in the LCR sequence were possibly co-variations.

Genetic variability and functional implication of the long control region in HPV-16 variants in Southwest China.

PMID: 28767682 2017 PloS one

Result: The other common LCR changes were A7730C, A7175C, T7177C, T7201C, C7270T, G7842A, C24T, A7287C and A7289C with mutation frequencies of approximately 71% (34/48), 65% (31/48), 65% (31/48), 65% (31/48), 65% (31/48), 65% (31/48), 65% (31/48), 63% (30/48) and 46% (22/48), respectively.

Result: When compared with the asymptomatic carriers, A7175C, T7177C, T7201C, C7270T, A7287C, A7289C,

PMID: 23852681 2013 Journal of medical virology

Abstract: Similar significant associations with cervical intraepithelial neoplasia grade 3 or worse were also observed for distinct nucleotide substitutions, including T178A/G, A647G, A7730C/G, T7781C, G7842A, and C24T/G.

[Human papillomavirus type 16 variant analysis of upstream regulatory region and E6, E7 oncogene from cervical cancer patients in Beijing].

PMID: 20423887 2010 Yi chuan

Abstract: A total of 8 hot mutation spot was identi-fied, which were URR G7521A (100%), C7435G (96.77%), C24T (45.16%), A7729C (45.16%), G7839A (45.16%), E6 T178G (41.94%), E7 A647G (45.16%), and T846C (45.16%).

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