Result: Compared with
E6, the
E7 gene is more conserved; the most common mutation site in
E7 was
A647G (18/75, 24%), and only one sample of
A645C and
A646C showed mutation.
Result: Nineteen single nucleotide changes were identified among the sequencing results for
E6 and
E7, including 14 missense mutations and five synonymous mutations: 11/14 missense mutations were distributed in the
E6 gene (
C168G,
G176A,
T178G,
T178A,
T183G,
A275G,
A2
HPV mutation literature information.
PMID: 
2019
Cancer cell international
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