Abstract: Of the mutations found in the
L1 gene, three novel nonsynonymous mutations of
C5640T,
A5641T and
G5642A were located within the region that encodes the binding domain of neutralizing antibodies against HPV 52.
Abstract: The genetic variations of HPV 52, including three novel nonsynonymous mutations of
C5640T,
A5641T and
G5642A in the
L1 gene and a novel CTT7681-7683 deletion in the
LCR, were first documented in strains from women in Northeast China.
Result: Among them, three (23.1%) novel mutations of
C5640T,
A5641T and
G5642A, which led to th