Discussion: In addition, Eur viruses have been divided into a few small branches, such as E-T350 (Ep), E-G350 (T350G), E-G131 (A131G) and E-C109 (T109C).
Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico.
Introduction: Other polymorphisms including A131G, G132C, C143G, G145T, G176A, T178G and C335T generate the amino acid changes R10G/I, Q14H/D, D25E/N, I27R and H78Y, respectively.
Analysis of mutations in the E6 oncogene of human papillomavirus 16 in cervical cancer isolates from Moroccan women.
Result: The other non-synonymous variants were R10I (G132T), R10G (A131G), D64E (T295G), Q14H (G145T) and A61G (C285G) and were seen in 23.3%, 6.8%, 6.8%, 1.9% and 1% of cases respectively.
Table: A131G
Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, China.
Result: The most remarkable difference between TSCC and CC was found with regard to the frequencies of the E-A131G variant causing a change from arginine to glycine in a.a.
Abstract: In particular, we describe methods for the identification of variation within the HPV-16 E5 open reading frame and for the detection of the nt 131 A-->G mutation of the E6 ORF, using restriction fragment length polymorphism assays.
Human papillomavirus type 16 E6 and E7 genotypes in head-and-neck carcinomas.
Abstract: Sequence analysis of the E6-E7 segments revealed three different HPV16 E6-E7 genotypes: the HPV16 prototype (6 of 21 cases), the E6 variant T350G (8 of 21 cases), and the E6-E7 variant A131G/C712A (7 of 21 cases).
Abstract: The E6 variants T350G and A131G have been associated with increased oncogenic potential in cervical cancer patients depending on host genetic factors.