Antiretroviral Drug Resistance Mutations among HIV Treatment Failure Patients in Tehran, Iran.
PMID: 29026792
2017
Iranian journal of public health
Table: Y181C
Prevalence of Pre-antiretroviral-Treatment Drug Resistance by Gender, Age, and Other Factors in HIV-Infected Individuals Initiating Therapy in Kenya, 2013-2014.
PMID: 29040633
2017
The Journal of infectious diseases
Abstract: PDR was defined as >=2% mutant frequency in a participant's HIV quasispecies at pol codons K103N, Y181C, G190A, M184 V, or K65R by oligonucleotide ligation assay and Illumina sequencing.
Upward trends of acquired drug resistances in Ethiopian HIV-1C isolates: A decade longitudinal study.
Discussion: Lastly, the study in one side identified an increasing common mutational pathways overtime with two thymidine non-analog (M184V and K65R) and three thymidine analog (D67N, K70R and K219E) major nucleoside reverse transcriptase inhibitor (NRTI)-associated DRMs and four major NNRTI-associated DRMs (K103N, Y181C, G190A, and V106M) which is consistent with previous studies.
Gag P2/NC and pol genetic diversity, polymorphism, and drug resistance mutations in HIV-1 CRF02_AG- and non-CRF02_AG-infected patients in Yaounde, Cameroon.
Discussion: In addition to the resistance mutations to NRTIs (M184V and the TAM T215F) and NNRTIs (L100I, Y181C, K103N, V108I, and Y188L) observed in naive subjects, these subjects on ART also had the TAMs D67N, K70R, and K219Q; and 9 of those 11 subjects had major resistance mutations to both NRTIs and NNRTIs.
Discussion: In the current study, analysis of RT and protease sequences from 109
Virological response, HIV-1 drug resistance mutations and genetic diversity among patients on first-line antiretroviral therapy in N'Djamena, Chad: findings from a cross-sectional study.
Result: Of note, Y181C/F and K103N were observed concomitantly in three (7%) cases.
Result: Out of the 43 sequences generated, the most prevalent DRMs were: 30% [13/43] K103N/S/E, 26% [11/43] Y181C/V/F/L, 2% [1/43] L100I, 2% [1/43] F227L and 2% [1/43] P225H, followed by other DRMs observed at lower rates.
Discussion: As levels of acquired HIVDR are higher to NNRTIs (32%) compared to NRTIs (29%), conferring high-level resistance to NVP and EFV (mainly due to K103N and Y181C), NRTIs are more prone for use in second-line co
HIV-1 viraemia and drug resistance amongst female sex workers in Soweto, South Africa: A cross sectional study.
Abstract: The observed mutations for NRTI were K65R, T215I and K219E (33.0% each) and for NNRTI: V106M, Y181C and Y188H (6.0% each).
[Analysis on HIV-1 subtypes and transmission clusters in newly reported HIV/AIDS cases in Yiwu, Zhejiang Province, 2016].
PMID: 29294588
2017
Zhonghua liu xing bing xue za zhi
Abstract: Seven cases with surveillance drug resistant mutations (SDRM) were found, including 5 cases of M46L (3.3%), and one case of F77L or Y181C.
SURVEILLANCE OF HIV-1 DRUG-RESISTANCE MUTATIONS IN THAILAND FROM 1999 TO 2014.
PMID: 29641878
2017
The Southeast Asian journal of tropical medicine and public health
Abstract: However, non-NRTI-associated mutations increased between 1999 and 2007,but have remained constant since, with Y181I/C the most (31.4%) prevalent.
Comparison of genotypic and virtual phenotypic drug resistance interpretations with laboratory-based phenotypes among CRF01_AE and subtype B HIV-infected individuals.
HIV mutation literature information.
PMID: 
2017
Iranian journal of public health
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