Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase.
PMID: 9837947
1998
The Journal of biological chemistry
Abstract: The K219A, Y115F, and Q151M mutants had no influence on the fidelity; Y183A, Y183F, K65A, and Q151N mutants exhibited higher fidelity on both RNA and DNA templates, while Y115A was less error-prone selectively on a DNA template.