literature

HIV mutation literature information.

HIV-1 Epidemiology, Genetic Diversity, and Primary Drug Resistance in the Tyumen Oblast, Russia.

PMID: 27957489 2016 BioMed research international

Result: The mutations with a low effect on the resistance to NNRTIs (E138A, V108I, and V90I) also had a low prevalence.

Viral Genetic Diversity and Polymorphisms in a Cohort of HIV-1-Infected Patients Eligible for Initiation of Antiretroviral Therapy in Abuja, Nigeria.

PMID: 25582324 2015 AIDS research and human retroviruses

Result: Among all the mutations detected, T74S (54.5%) in PR and E138A (17%), V179I (16%), followed by V118I and V179E (14% each) in RT were the most prevalent, while T69NS, V90I, and V106I were present at only 5% each.

Result: The prevalence for T69NS, V90I, and V106I was 1.5%, respectively.

Result: We also detected NRTI selected mutations M41L, E44D, T69ANS,

PMID: 25630709 2015 Global health action

Table: V90I

A post-partum single-dose TDF/FTC tail does not prevent the selection of NNRTI resistance in women receiving pre-partum ZDV and intrapartum single-dose nevirapine to prevent mother-to- child HIV-1 transmission.

PMID: 25940687 2015 Journal of medical virology

Result: (K103N and Y188C, K103N and G190AG, A98G and G190AG and Y188C and V90I).

Result: V90I and E138A were detected in each of two patients.

In vitro selection of HIV-1 CRF08_BC variants resistant to reverse transcriptase inhibitors.

PMID: 25482475 2015 AIDS research and human retroviruses

Abstract: As expected, M184I alone, or with V90I or D67N, decreased 3TC susceptibility by over 1,000-fold.

Abstract: Initial mutations, in combination with other previously reported substitutions (K20R, D67N, V90I, K101R/E, V106I/A, V108I, F116L, E138R, A139V, V189I, G190A, D218E, E203K, H221Y, F227L, N348I, and

Comparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission.

PMID: 26469189 2015 PloS one

Result: Twenty-eight NVP-selected mutations (V90I, K101E, K103N/R, V106A/I/M, V108I, E138A/G/K/R, Y181C, Y188C, G190A or P225H) were detected in 19 samples at levels of 1.1% to 99.1%.

Table: V90I

Low Incidence of HIV-1C Acquired Drug Resistance 10 Years after Roll-Out of Antiretroviral Therapy in Ethiopia: A Prospective Cohort Study.

PMID: 26512902 2015 PloS one

Abstract: The NNRTIs resistance associated mutations were K103N (n = 2), V106M, Y181S, Y188L, V90I, K101E and G190A (n = 1 each).

Result: Other NNRTIs associated mutations Y181S, Y188L, V90I, K101E and G190A were observed in one patient each.

Table: V90I

HIV Drug Resistance Surveillance in Honduras after a Decade of Widespread Antiretroviral Therapy.

PMID: 26558396 2015 PloS one

Table: V90I

Outcome of patients on second line antiretroviral therapy under programmatic condition in India.

PMID: 26572102 2015 BMC infectious diseases

Table: V90I

Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity.

PMID: 25575025 2014 Retrovirology

Table: V90I

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