Abstract: We have also obtained the crystal structures of three mutant forms of NL4-3 protease containing one (V82A), three (V82A, M46I, F53L) and six (V82A, M46I, F53L, V77I, L24I, L63P) point mutations in complex with TL-3.
Short communication: low prevalence of genotypic drug resistance mutations among antiretroviral-naive HIV type 1 patients in Malaysia.
PMID: 16478392
2006
AIDS research and human retroviruses
Abstract: Amino acid substitutions I13V, E35D, and M36I were associated with CRF01_AE while L63P, V77I, and I93L were associated with subtype B.
HIV-1 genetic diversity and genotypic drug susceptibility in the Republic of Georgia.
PMID: 16706626
2006
AIDS research and human retroviruses
1Abstract: This ""V77I haplotype"" marks one particular genetic lineage of the epidemic in the former Soviet Union."
Abstract: Twelve of the subtype A strains (25%) contained the secondary protease inhibitor mutation V77I and 9 also had two other silent mutations.
Characterization of drug-resistance mutations in HIV-1 isolates from non-HAART and HAART treated patients in Burkina Faso.
[Background study of HIV-1 drug resistant mutations in treatment-naive patients in liaoning province].
PMID: 17121220
2006
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
Abstract: Minor resistance mutation rate to protease inhibitors was 100%, including types of L63P (60.4%), V77I (60.4%), M36I/V (31.9%), A71V/T (22.0%), L10I (8.8%), and K20R (6.6%).
Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs.
PMID: 19825125
2005
Journal of the International AIDS Society
Table: V77I
Analysis of drug resistance-associated mutations in treatment-naive individuals infected with different genetic forms of HIV-1 circulating in countries of the former Soviet Union.
Abstract: V77I substitution in PR was found in 47.8% of samples.
[Genotypic antiretroviral resistance testing and phylogenetic analysis of protease and reverse transcriptase in antiretroviral drug-naive AIDS patients in Henan province].
PMID: 16053762
2005
Zhonghua liu xing bing xue za zhi
Abstract: Minor mutation rate of resistance was 100%, including types of L63PS (36/36), I93L (35/36), V77IL (34/36), A71IVT (10/36) and D60E (2/36).
[Protease and reverse transcriptase genetic polymorphism in HIV type 1 subtype A variants predominating in cis countries].
Abstract: However, high frequencies of secondary mutations V77I in protease and A62V in RT (67% H 63%, respectively) linked to each other in most cases were observed.
Abstract: In addition, three other variants were found: viruses not containing the substitutions V77I or A62V, and variants bearing only one of them.
Abstract: The HIV-1 isolates bearing both substitutions (MutV77I/A62V) were also characterized by the presence of several synonymous mutations, suggesting common origin for these viruses.
Antiretroviral resistance and genetic diversity of human immunodeficiency virus type 1 isolates from the Federal District, Central Brazil.
PMID: 15761606
2004
Memorias do Instituto Oswaldo Cruz
Abstract: Minor mutations were also found at the protease gene: L10I/V (7%), K20M (2%), M36I (11%), L63P (20%), A71T (2%), and V77I (7%).
HIV mutation literature information.
PMID: 
2006
Journal of molecular biology
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