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 HIV mutation literature information.


  Combating HIV resistance - focus on darunavir.
 PMID: 19209258       2008       Therapeutics and clinical risk management
Abstract: Darunavir resistance-associated mutations have been defined as V11I, V32I, L33F, I47V, I50V, I54L/M, G73S, L76V, I84V, and L89V.


  Pattern and impact of emerging resistance mutations in treatment experienced patients failing darunavir-containing regimen.
 PMID: 18690163       2008       AIDS (London, England)
Abstract: Emergence of DRV-associated-resistance mutations was observed in 72% (18/25) of patients, at codons L89I/M/V (32%), V32I (28%), V11I (20%), I47V/A (20%), I54L/M (20%), L33F/I (16%) and I50V (16%).


  Prevalence of darunavir resistance mutations in HIV-1-infected patients failing other protease inhibitors.
 PMID: 17646201       2007       The Journal of antimicrobial chemotherapy
Abstract: For minor darunavir resistance mutations, the rates were V11I 3.3%, V32I 3.9%, L33F 11%, I47V 2.1%, I54L 2.3%, G73S 12.8% and L89V 2.4%.


  Variability of the human immunodeficiency virus type 1 polymerase gene from treatment naive patients in Accra, Ghana.
 PMID: 17827059       2007       Journal of clinical virology
Abstract: The L10I, L10V, V11I and E35G minor mutations were seen in four patients, while the V179E was observed in a patient with subtype G.



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