HIV mutation literature information.


  Polymorphisms and Mutational Covariation Associated with Death in a Prospective Cohort of HIV/AIDS Patients Receiving Long-Term ART in China.
 PMID: 28099515       2017       PloS one
Result: For example, M41L and D67N had 16 (D218E, E44A, G190S, G196E, H221Y, I142V, K101E, L210W, L228R, L74V, M184V, R211K, T215F, V108I, V118I, and V179I) and nine (E44A, H208Y, H221Y, K70R, L210W


  HIV drug resistance in HIV positive individuals under antiretroviral treatment in Shandong Province, China.
 PMID: 28750025       2017       PloS one
Table: V118I


  HIV-1 Epidemiology, Genetic Diversity, and Primary Drug Resistance in the Tyumen Oblast, Russia.
 PMID: 27957489       2016       BioMed research international
Result: Of the mutations influencing NRTI therapy, only the V118I mutation (of the TAM set, efficient only in combination with other resistance mutations) was found.


  Clinical, virological and phylogenetic characterization of a multiresistant HIV-1 strain outbreak in naive patients in southern Spain.
 PMID: 26483513       2016       The Journal of antimicrobial chemotherapy
Abstract: BACKGROUND: We describe the characteristics of an HIV-1 strain with six viral reverse transcriptase mutations (D67N, T69N/D, V118I, V179D, T215S and K219Q), which we have called the Malaga strain.


  Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.
 PMID: 26850643       2016       Nucleic acids research
Result: V118I occurs in combination with multiple TAMs.


  Lack of integrase inhibitors associated resistance mutations among HIV-1C isolates.
 PMID: 26626277       2015       Journal of translational medicine
Result: A subtype C-specific polymorphism associated with NRTIs (V118I) was detected in one patient.


  Viral Genetic Diversity and Polymorphisms in a Cohort of HIV-1-Infected Patients Eligible for Initiation of Antiretroviral Therapy in Abuja, Nigeria.
 PMID: 25582324       2015       AIDS research and human retroviruses
Result: Among all the mutations detected, T74S (54.5%) in PR and E138A (17%), V179I (16%), followed by V118I and V179E (14% each) in RT were the most prevalent, while T69NS, V90I, and V106I were present at only 5% each.
Result: We also detected NRTI selected mutations M41L, E44D, T69ANS, V75M, and V118I, and NNRTI mutations V90I,


  Epidemiological and molecular characteristics of HIV infection among money boys and general men who have sex with men in Shanghai, China.
 PMID: 25653132       2015       Infection, genetics and evolution
Result: Several minor mutations were detected in the protease (PR) region of the pol gene: L10I (3.8%), V11I (1.9%), L33F (1.9%) and A71T/V (17.3%); and several others were detected in the reverse transcriptase (RT) region of the pol gene: T69A (1.9%), V118I (11.5%), L210M (1.9%), V179I (11.5%) and K101Q (1.9%).


  Effectiveness of a Treatment Switch to Nevirapine plus Tenofovir and Emtricitabine (or Lamivudine) in Adults with HIV-1 Suppressed Viremia.
 PMID: 26107265       2015       PloS one
Table: V118I


  Comparison of 454 Ultra-Deep Sequencing and Allele-Specific Real-Time PCR with Regard to the Detection of Emerging Drug-Resistant Minor HIV-1 Variants after Antiretroviral Prophylaxis for Vertical Transmission.
 PMID: 26469189       2015       PloS one
Method: M19921) and a mutant pNL4.3 derived clone that harbours seven resistance mutations in the RT (M41L, A62V, A98G, K103N, V118I, L210W, T215Y).



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