Evolution and viral characteristics of a long-term circulating resistant HIV-1 strain in a cluster of treatment-naive patients.
PMID: 23467175
2013
The Journal of antimicrobial chemotherapy
Abstract: In vivo evolution showed a mixture with wild-type (T215S/T) in only one untreated patient more than 6 years after diagnosis.
Abstract: We observed eight therapy-naive patients infected with HIV harbouring four mutations at nucleoside reverse transcriptase inhibitor (NRTI) resistance-related positions: M41L, T69S, L210E and T215S.
HIV-1 drug resistance-associated mutations among antiretroviral-naive Thai patients with chronic HIV-1 infection.
Abstract: DRAMs to NRTIs were M184V (0.3%) and T215S (0.3%).
The prevalence of transmitted drug resistance in newly diagnosed HIV-infected individuals in Croatia: the role of transmission clusters of men who have sex with men carrying the T215S surveillance drug resistance mutation.
PMID: 22906365
2013
AIDS research and human retroviruses
Abstract: A total of 12 transmission pairs and eight distinct transmission clusters were identified with the largest cluster harboring sequences from 19 patients; among them all but two were carrying the T215S mutation.
Abstract: The most frequently found NRTI SDRM was T215S (17 of 118 patients, 14.4%).
HIV type 1 molecular epidemiology in pol and gp41 genes among naive patients from Mato Grosso do Sul State, central western Brazil.
PMID: 21790471
2012
AIDS research and human retroviruses
Abstract: The Pol-RT V75M mutation was detected in two homosexual partners; one patient had the T215S revertant mutation.
HIV-1 subtype D infections among Caucasians from Northwestern Poland--phylogenetic and clinical analysis.
Abstract: Baseline drug resistance to nucleoside reverse transcriptase inhibitors was observed in 54.5% of cases (mutations: M41L, K103N, T215S/D) with evidence of clustering, no baseline integrase or protease resistance and infrequent non-R5 tropism (13.6%).
Table: T215S
Zidovudine (AZT) monotherapy selects for the A360V mutation in the connection domain of HIV-1 reverse transcriptase.
[Survey of HIV drug resistance threshold in Zhejiang province from 2009 to 2011].
PMID: 22943898
2012
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
Abstract: SDRMs for protease inhibitor (PI), nucleotide HIV-reverse transcriptase inhibitor (NRTI) and non-NRTI (NNRTI) (L90M, T215S and Y188L) were all found in one case.
Differential in vitro kinetics of drug resistance mutation acquisition in HIV-1 RT of subtypes B and C.
Result: It must be noted, that three of the patients with developed drug resistance were heavily experienced with reverse transcriptase (RT) and protease (PR) mutations (patient 1: RT: M41L, K103N, M184V, T215S; PR: L10I; patient 2: PR: M41L, V118I, K103N, M184V, L210W, T215S, RT: L10I,
HIV mutation literature information.
PMID: 
2013
The Journal of antimicrobial chemotherapy
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