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 HIV mutation literature information.


  HIV-1 Antiretroviral Drug Resistance Mutations in Treatment Naive and Experienced Panamanian Subjects: Impact on National Use of EFV-Based Schemes.
 PMID: 27119150       2016       PloS one
Discussion: Thus, the impact of TAMs need to be better evaluated in coming years since HIV-infected subjects with mutations M184V alone, P119S/T165A/M184V combined or T69 insertion complex, including T210W and T215Y, may have significantly decreased susceptibility to the novel drug Ed4T.


  Differential in vitro kinetics of drug resistance mutation acquisition in HIV-1 RT of subtypes B and C.
 PMID: 23056372       2012       PloS one
Introduction: Two distinct TAM resistance pathways can be observed: TAM-1 (M41L, T210W and T215Y) and TAM-2 (D67N, K70R, T215F and K219Q).



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