Abstract: Among them, 7 polymorphisms (L74I, K103N, V106A, Y181C, G190A, T215I and P225H) were known to be drug resistance mutations, 7 polymorphisms (E6D, E35D, S37N, I93L, E169D, T200V and T200E were considered to be potential drug resistance mutations, and 6 polymorphisms (T39A, K43E, S68N, Q197K, T200V and E22
Characteristics of HIV-1 natural drug resistance-associated mutations in former paid blood donors in Henan Province, China.
Abstract: Polymorphism mutation sites with mutation rates in the RT region higher than 60.0% were: I135A/L/M/R/T/V 93.5%, T200A/E/I/P/V 89.7%, Q278E/K/N/T 88.8%, S162C/Y 82.2%, and K277R/S 66.4%.
Result: The sites with mutation rates higher than 60.0% included: I135A/L/M/R/T/V 93.5% (100/107), among which I135V was 80.4% (86/107); T200A/E/I/P/V 89.7% (96/107), among which T200A was 81.3% (87/107); Q278E/K/N/T 88.8% (95/107), among which
HIV mutation literature information.
PMID: 
2017
PloS one
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