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 HIV mutation literature information.


  Persistence of HIV-1 transmitted drug resistance mutations.
 PMID: 23904291       2013       The Journal of infectious diseases
Table: N83D


  Trends in Genotypic HIV-1 Antiretroviral Resistance between 2006 and 2012 in South African Patients Receiving First- and Second-Line Antiretroviral Treatment Regimens.
 PMID: 23840622       2013       PloS one
Table: N83D


  "Description of the L76V resistance protease mutation in HIV-1 B and ""non-B"" subtypes."
 PMID: 23349869       2013       PloS one
Method: In our study, samples with at least one of the major PI RAM of the IAS-USA list as follows: D30N, V32I, M46I/L, I47A/V, G48V, I50L/V, I54L/M, Q58E, T74P, L76V, V82A/F/L/T/S, N83D, I84V, N88S, L90M were considered as PI-resistant issued from PI-experienced patients.


  Tenofovir-based regimens associated with less drug resistance in HIV-1-infected Nigerians failing first-line antiretroviral therapy.
 PMID: 23079810       2013       AIDS (London, England)
Result: Three patients had selected IAS PI major mutations (I50V, N83D, I84V and L90M).


  Update of the drug resistance mutations in HIV-1: December 2010.
 PMID: 21245516       2010       Topics in HIV medicine
Abstract: In addition, the tipranavir/ritonavir N83D mutation designation was changed to boldface to indicate its recognition as a major mutation rather than a minor mutation.


  Tipranavir: a new protease inhibitor for the treatment of antiretroviral-experienced HIV-infected patients.
 PMID: 17425479       2007       Expert opinion on pharmacotherapy
Abstract: The TPV mutation score includes L10V, I13V, K20M/R/V, L33F, E35G, M36I, K43T, M46L, I47V, I54A/M/V, Q58E, H69K, T74P, V82L/T, N83D and I84V.


  Tipranavir: a ritonavir-boosted protease inhibitor.
 PMID: 16060700       2005       Drugs
Abstract: Analysis of clinical isolates from treatment-experienced patients identified the following tipranavir resistance-associated HIV protease mutations: L10V, I13V, K20M/R/V, L33F, E35G, M36I, K43T, M46L, I47V, I54A/M/V, Q58E, H69K, T74P, V82L/T, N83D, I84V.



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