literature

HIV mutation literature information.

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.

PMID: 18025130 2007 The Journal of experimental medicine

Result: Mutations at position 2 in this epitope, which typically occur late during the disease and subsequent to the L6M mutation, are also strongly associated with HLA-B2705 expression and have been shown to reduce binding to HLA-B2705.

Figure: (C) Mean fluorescence intensity of the B2705-KK10 WT and Figure: Dot plots indicate the proportion of allogenic CD4 or CD8 T cells after a 6-d exposure to MDDCs in the presence of HLA-B27-KK10 WT or L6M pentamers.

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