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 HIV mutation literature information.


  Protein structure and oligomerization are important for the formation of export-competent HIV-1 Rev-RRE complexes.
 PMID: 18218716       2008       Protein science
Abstract: The oligomeric assembly of Rev-L18T is impaired but exhibits minor defects in structure and retains a basal level of activity in vivo.
Abstract: The prevalence of L18T in infected individuals suggests a positive selection mechanism for L18T modulation of Rev activity that may delay the onset of AIDS.



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