literature

HIV mutation literature information.

[Prevalence of primary antiretroviral resistance among HIV infected patients in Chile].

PMID: 20919475 2010 Revista medica de Chile

Abstract: Of these, the most common were L63P/T (38 patients), L10I/V (27 patients) and V77I (26 patients).

HIV-1 drug resistance transmission networks in southwest Switzerland.

PMID: 20860534 2010 AIDS research and human retroviruses

Abstract: Resistant mutations to PIs consisted of L10V and accessory mutations 16E and 60E present in all F1 clades.

HIV drug resistance surveillance using pooled pyrosequencing.

PMID: 20174661 2010 PloS one

Table: L10V

High level of primary drug resistance in Mali.

PMID: 20146734 2010 HIV medicine

Abstract: Taking into consideration other polymorphisms in protease such as L10I/V and 33F, primary resistance could reach 28.7% (95% CI 19.9-37.5%).

HIV-1 primary and secondary antiretroviral drug resistance and genetic diversity among pregnant women from central Brazil.

PMID: 20087934 2010 Journal of medical virology

Abstract: Naive patients had accessory mutations in the PR gene [A71T (1/6), L10V (2/6), L10I (3/6)] and in the RT gene [V118I (2/6), V179D (1/6), V106I (1/6), K101Q (1/6), H221Y (1/6)].

Protease polymorphisms in HIV-1 subtype CRF01_AE represent selection by antiretroviral therapy and host immune pressure.

PMID: 20009919 2010 AIDS (London, England)

Abstract: Three polymorphisms (L10 V, K20RMI and I62 V) were associated with the presence of a major PRAM (P < 0.05).

Virological efficacy and emergence of drug resistance in adults on antiretroviral treatment in rural Tanzania.

PMID: 19583845 2009 BMC infectious diseases

Table: L10V

Antiretroviral drug susceptibility among drug-naive adults with recent HIV infection in Rakai, Uganda.

PMID: 19276794 2009 AIDS (London, England)

Table: L10V

Emergence of multiclass drug-resistance in HIV-2 in antiretroviral-treated individuals in Senegal: implications for HIV-2 treatment in resouce-limited West Africa.

PMID: 19143530 2009 Clinical infectious diseases

Result: Naturally occurring HIV-2 PR polymorphisms that are associated with PI resistance in HIV-1 were common; major (V32I/L, M46I/V, and I47V) and minor (L10V/I, E35G/R, Q58E, A71V/I, and G73A/T) PI resistance mutations were found in all 23 patients.

Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure.

PMID: 18992847 2009 Infection, genetics and evolution

Abstract: In untreated patients, mutations L10V, K20R, and M36I were more frequent in subtype F1, while L63P, A71T, and V77I were more prevalent in subtype B.

Method: Mutations L10F/I/R/V, K20M/R, L24I, L33F, M36I, F53L, I54V/L/A/M/T/S, L63P, A71V/T, G73C/S/T/A, V77I and N88D/S were considered as minor resist

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