Human immunodeficiency virus type 1 proteinase resistance to symmetric cyclic urea inhibitor analogs.
PMID: 9371337
1997
Antimicrobial agents and chemotherapy
Abstract: Virus with the same mutation is also resistant, although the double mutation L10F/I84V confers even greater resistance.
Kinetic characterization of human immunodeficiency virus type-1 protease-resistant variants.
PMID: 8663409
1996
The Journal of biological chemistry
Abstract: We have characterized recombinant HIV-1 proteases that contain these mutations either individually (L10F, M46I, I47V, I50V) or in combination (the double mutant L10F/I50V and the triple mutant M46I/I47V/I50V).