Abstract: Based on these observations, we propose that although F423Y, I595F and K655E may all affect the presentation of the 2F5 and 4E10 epitopes, natural immune mimicry is rare only for the I595F effect.
Abstract: Thus, it seems that in addition to restricting AI resistance development, incorporation of I595F into an appropriate vehicle could elicit a novel antiviral response to improve vaccine efficacy.
Abstract: We also observed that I595F did not substantially increase envelope sensitivity to HIV-infected patient sera.
Abstract: We report on three such mutations: F423Y (gp120 CD4 binding pocket) and
HIV mutation literature information.
PMID: 
2010
Virology
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