Abstract: Current
PI therapy (P = 0.002) and indinavir administration (P < 0.001), >5 LPV/r mutations (P < 0.0012), and detection of
L10FIRV,
K20MR,
M46IL,
I54VL,
A71VT,
G73SA,
V82AFTS,
I84V, and
M90L were associated with LPV resistance in univariate analysis.
Abstract: Factors independently associated with LPV resistance were
K20MR (odds ratio [OR], 13.9; 95% confidence interval [CI], 1.3-145.1; P = 0.028),
I54VL (OR, 131.7; 95% CI, 10.5-1654.7; P < 0.001),
G73SA (OR, 19.2; 95%