literature

HIV mutation literature information.

Polymorphisms and Mutational Covariation Associated with Death in a Prospective Cohort of HIV/AIDS Patients Receiving Long-Term ART in China.

PMID: 28099515 2017 PloS one

Abstract: Among them, 7 polymorphisms (L74I, K103N, V106A, Y181C, G190A, T215I and P225H) were known to be drug resistance mutations, 7 polymorphisms (E6D, E35D, S37N, I93L, E169D, T200V and T200E were considered to be potential drug resistance mutations, and 6 polymorphisms (T39A, K43E, S68N, Q197K, T200V and E22

Persistence of frequently transmitted drug-resistant HIV-1 variants can be explained by high viral replication capacity.

PMID: 25575025 2014 Retrovirology

Table: E169D

Precise identification of a human immunodeficiency virus type 1 antigen processing mutant.

PMID: 17108020 2007 Journal of virology

Abstract: Here we investigate the association between E169D and HLA-B*0702 for immune escape via the SM9 epitope.

Abstract: Polymorphism E169D in HIV-1 reverse transcriptase (RT) is significantly associated with HLA-B*0702 in HIV-1-infected individuals.

Abstract: The E169D polymorphism also maps within and abrogates the recognition of an HLA-A*03-restricted RT epitope MR9.

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