Abstract: In addition, ELISA revealed reduced HBs antigenicity of two mutants, W1S N146G and W1S Q129R/G145R.
Abstract: On the other hand, the single mutants of W1S, P120K and T123D, significantly impaired the reactivity, while W1S-aW3S and the double mutant of W1S, P120K/T123D, resulted in a complete loss of antigenicity.
Introduction: In this study, we cloned the ORFs of three wild-type HBsAgs, designated W1S, W3S and adr4 (a
HBV mutation literature information.
PMID: 
2017
PloS one
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