Prevalence, genotype distribution and mutations of hepatitis B virus and the associated risk factors among pregnant women residing in the northern shores of Persian Gulf, Iran.
Result: T1753A, A1761C, and G1764A mutations caused the conversion of Ile Asn at amino acid 127 (I127N), Lys Gln at amino acid 130 (K130Q), and Val Leu at amino acid 131 (V131L) of the X protein, respectively (S3 Fig).
The Correlation Between Hepatitis B Virus Precore/Core Mutations and the Progression of Severe Liver Disease.
PMID: 30406036
2018
Frontiers in cellular and infection microbiology
Introduction: Mutations within the X gene, including V5M, I127T, K130M, and V131I/L, are risk factors for HCC and may promote the progression of liver degradation (Kim et al.,).
Hepatitis B virus (HBV) X gene mutations and their association with liver disease progression in HBV-infected patients.
Abstract: One double mutation (K130M+V131I) and two triple mutations (I127T+K130M+V131L and K130M+V131I+F132Y) were observed, with significant rising prevalence through progressive clinical phases of liver disease to HCC.
HBV mutation literature information.
PMID: 
2022
PloS one
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