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 HBV mutation literature information.


  Clinical and virological features of occult hepatitis B in patients with HBsAg seroclearance post-treatment or spontaneously.
 PMID: 24119014       2014       Liver international
Abstract: CONCLUSIONS: One mutation, C3050T (preS1T68I), decreased S promoter activity; nevertheless, other factors may play more important role in the clearance of HBsAg in these OHB patients.
Abstract: One mutation in surface promoter/polymerase region, C3050T (preS1T68I), was identified to be associated with the seroclearance of HBsAg in six cases.


  Naturally occurring hepatitis B virus B-cell and T-cell epitope mutants in hepatitis B vaccinated children.
 PMID: 24379746       2013       TheScientificWorldJournal
Result: Fifteen substitutions outside the B- and T-cell epitopes (Q10 K, M12T, N15S, N20S, A54E, H56N, V60A, S62A, T68I, Q82S, L84I, L85F, A90V, V172A, and L173P) were found.



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