HBV mutation literature information.


  Molecular and serological characterization of hepatitis B vaccine breakthrough infections in serial samples from two plasma donors.
 PMID: 30943997       2019       Virology journal
Result: PreS2 (aa 1-55) substitutions were: V32 L, N33S, A35V, N37 T, A47S, T49I, V53A, T54P.


  Occult HBV among Anti-HBc Alone: Mutation Analysis of an HBV Surface Gene and Pre-S Gene.
 PMID: 28332361       2017       Yonsei medical journal
Result: T49I was seen in three controls (C4, C6, and C7), but was not observed in the occult HBV infection group.


  Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations.
 PMID: 20119580       2010       Journal of Korean medical science
Result: V32A, I45T, and T49I mutations were detected in the patients with HCC, both groups equally.
Discussion: In addition, V32A, I45T, and T49I mutations at Pre-S2 were detected in the HCC patients only.



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