HBV mutation literature information.


  A336C/A336T/T337C variations in HBV core gene and spontaneous hepatitis B e antigen loss in chronic hepatitis B patients.
 PMID: 21569538       2011       Virology journal
Abstract: A336C/A336T/T337C variations occurred in 40/166(24.1%) chronic hepatitis B patients.
Abstract: BACKGROUND: A336C/A336T/T337C variations in HBV core gene were demonstrated to relate to the decreases in serum HBV DNA levels and HBV replication in chronic hepatitis B patients.
Abstract: CONCLUSION/SIGNIFICANCE: A336C/A336T/T337C were naturally occurring polymorphisms in HBV core gene, and moreover, the presence of C336/T336/C337 variants was first demonstrated to be an independent factor associating with spontaneous


  Clinical significance of a set of single nucleotide polymorphisms of hepatitis B virus core gene in Chinese Han patients with chronic hepatitis B.
 PMID: 18814242       2008       Journal of medical virology
Abstract: 5 SNPs, A261T, A336C, A336T T337C and T385C, were found to be associated with RFLP patterns change and only SNP A336C or A336T caused the substitution of Glu-83 with Asp in HBcAg.



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