Result: Our unbiased approach led us to the discovery of additional variants highly associated with patient's HBeAg status: G1899A, A1838G, T2045A, G2345A, G2352A, T2441C, A2189C, T2443C, C1962A, G2237C, and others (LRT; p < 9.55 x 10-13.
Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: a meta-analysis.
PMID: 19574418
2009
Journal of the National Cancer Institute
Table: T2441C
Genotype-specific genomic markers associated with primary hepatomas, based on complete genomic sequencing of hepatitis B virus.
Abstract: HCC-related mutations T31C, T53C, and A1499G were associated with HBV subgenotype Ce, and mutations G1613A, G1899A, T2170C/G, and T2441C were associated with HBV subgenotype Cs.