Abstract: A newly developed PCR system detecting
T1961V showed that HBV/B1 and low viral load were independent factors for the mutation among
chronic infection patients.
Abstract: RESULTS: In the analysis of full-genome sequences of HBV/B1 (FHB, n=11; non-FHB, n=35) including those from the databases, mutations at nt 1961 [
T1961V (not T)] and nt 1962 [
C1962D (not C)], which change S21 in the
core protein, were found more frequently in
FHB than in non-FHB (100% vs.