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 HBV mutation literature information.


  Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia.
 PMID: 29408943       2018       PloS one
Table: T1758C


  Mutations of Basal core promoter and precore regions in hepatitis B virus genotypes B and C.
 PMID: 25741368       2015       Hepatitis monthly
Table: T1758C


  Associations between hepatitis B virus basal core promoter/pre-core region mutations and the risk of acute-on-chronic liver failure: a meta-analysis.
 PMID: 26063382       2015       Virology journal
Method: The following mutation sites were also detected in the included studies: G1613A, C1653T, 1752G, T1754V, T1753V/A1762T/G1764A, T1758C, G1764A/C1766T/T1768A, T1770A, 1773 T, G1775A, C1799V, T1800C, T1803C, G1809T, A1814C, A1837G, A1846G, T1853C,  PMID: 24282424       2013       Hepatitis monthly
Result: In addition, since BCP/PC mutations of T1754G, T1758C, C1766T, T1768A, G1862T, and T1858C were observed only in 7, 5, 7, 4, 1, and 4 of ACLF patients, respectively, these mutations were not included in further analysis.


  Features and clinical implications of hepatitis B virus genotypes and mutations in basal core promoter/precore region in 507 Chinese patients with acute and chronic hepatitis B.
 PMID: 20080060       2010       Journal of clinical virology
Abstract: CONCLUSION: Patients with genotype B virus, BCP/PC wild-type virus or T1758C mutant virus were more susceptible to develop AHB, whereas high prevalence of the BCP/PC mutations was associated with CHB development.
Abstract: Interestingly, T1758C and A1762T/G1764A appeared mutual restraint.
Abstract: Significantly lower prevalence of A1762T, G1764A, G1896A, and G1899A but higher prevalence of T1758C



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