Abstract: Compared with the wild type
X promoter, the mutant type
X promoters, M1 (
G1317A), M2 (
T1341C), and M4 (
T1341G) showed increases in activity of 2.3, 3.8, and 1.4 times, respectively, in HepG2 cells.
Abstract: Substitutions and deletion of nucleotides of the HBV genome, especially the
pre-S2 deletion and
G1317A and
T1341C/A/G mutations may be useful markers for predicting the development of
HCC.
Abstract: The number of nucleotide and amino acid substitutions in most regions was higher in the
HCC group than in the non-
HBV mutation literature information.
PMID: 
2007
Cancer science
