HBV mutation literature information.


  Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients.
 PMID: 35390033       2022       PloS one
Table: T118M


  Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutations.
 PMID: 32994690       2020       World journal of gastroenterology
Abstract: In particular, these mutations were sQ101H/K/R, sS114A/L/T, sT118A/K/M/R/S/V, sP120A/L/Q/S/T, sT/I126A/N/P/S, sM133I/L/T, sC137W/Y, sG145A/R, and sA159G/V.
Result: In particular, mutations were detected in 67/63


  Nearly half of Ultrio plus NAT non-discriminated reactive blood donors were identified as occult HBV infection in South China.
 PMID: 31269905       2019       BMC infectious diseases
Abstract: Most OBI strains were wild-type HBV, but some substitutions V168A, S174 N, V177A, Q129R/L/H, G145A/R in S region of genotype B (OBIB) and T47K/V/A, P49H/L, Q101R/H/K, S174 N, L175S, V177A, T118 M/R/K, G145R/A/K/E, R160K/N in S region of genotype C (OBIC) strains were identified in high frequency.


  Nucleotide Substitutions in Hepatitis B Viruses Derived from Chronic HBV Patients.
 PMID: 31308922       2019       Mediterranean journal of hematology and infectious diseases
Result: Five (5) mutations were detected within the surface gene in the patients (F8L, T118M, E164D, T189I, and W196L).
Result: The frequency of mutations in the MHR was seen in 18.0% (6/33) of isolates (T118M, E164D).


  Analysis of HBV basal core promoter/precore gene variability in patients with HBV drug resistance and HIV co-infection in Northwest Ethiopia.
 PMID: 29408943       2018       PloS one
Table: T118M


  The Thr to Met substitution of amino acid 118 in hepatitis B virus surface antigen escapes from immune-assay-based screening of blood donors.
 PMID: 26873737       2016       The Journal of general virology
Abstract: A mutagenesis assay indicated that the Thr to Met substitution at aa 118 was the determinant for escape from HBsAg ELISA detection.


  Decreased antigenicity profiles of immune-escaped and drug-resistant hepatitis B surface antigen (HBsAg) double mutants.
 PMID: 24053482       2013       Virology journal
Abstract: All five ELISA kits manifested similar avidity, which were demonstrated by the slope of the curves, for the sT118M mutant, and sT118M-rtM204I (sT118M-sI195M) and sT118M-rtM204V (sT118M-sW196S) double mutants, suggesting that drug-resistant YMDD mutants caused negligible losses in the antigenicity of immune-escaped


  Hepatitis B surface antigen variants in voluntary blood donors in Nanjing, China.
 PMID: 22500577       2012       Virology journal
Result: D99N, Y100F, Q101R/H, L110I, T113S, S114T, S117T, T118M, I126T/V, W165L, and V168A, which may be associated with antigenicity of HBsAg.



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