Discussion: The
G72* and
Q121* nonsense mutations in the
preS region could explain the lack of
L protein expression and
HBsAg negative phenotype of clones 12.1, 12.3, 8.3, and 8.4, while the
C69* and
S61* nonsense mutations in the
S region were confirmed to abolish
HBsAg production.
HBV mutation literature information.
PMID: 
2017
Virus research
