literature

HBV mutation literature information.

In silico functional and structural characterization of hepatitis B virus PreS/S-gene in Iranian patients infected with chronic hepatitis B virus genotype D.

PMID: 32695898 2020 Heliyon

Discussion: (2013) have similarly detected such mutations (S45 T/A, N131T, I194V, and S207N) in the S region and recommended further research in this domain.

Discussion: In fact, concerning our sequences, several immune epitope mutations including S45T, T113S, N131T, I194V and P142L in MK355500 and S207N in MK355501 were detected in S gene.

Naturally occurring hepatitis B virus B-cell and T-cell epitope mutants in hepatitis B vaccinated children.

PMID: 24379746 2013 TheScientificWorldJournal

Abstract: Several immune-epitope mutants, such as S45T/A, N131T, I194V, and S207N in S, were detected in all isolates.

Conclusion: Several immune-epitope mutants, such as S45T/A, N131T, I194V, and S207N in S, were detected in all isolates and needed to explore their role in HBV infection.

Result: Four replacements (S45T/A, N131T, I194V, and S207N) within the immune epitopes were observed in all isolates.

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