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 HBV mutation literature information.


  Precore/core mutations of hepatitis B virus genotype D arising in different states of infection.
 PMID: 35415256       2022       Clinical and experimental hepatology
Table: S21T


  Naturally occurring core immune-escape and carboxy-terminal mutations runcations in patients with e antigen negative chronic hepatitis B.
 PMID: 26201521       2012       Hepatology international
Abstract: CONCLUSION: Core immune-escape mutations cT12S, cS21T, cT67P, cE113D, and cP130T/Q are significantly higher in decompensated liver disease patients and could influence the severity of liver disease in HBeAg -ve CHB patients.
Abstract: Three core immune escape mutations were significantly higher in patients with coexisting precore stop codon compared with patients without


  CTL escape mutations of core protein are more frequent in strains of HBeAg negative patients with low levels of HBV DNA.
 PMID: 19748824       2009       Journal of clinical virology
Result: Substitutions of Ser21 to Thr21 or Ala21 were never accompanied with T1762A1764 core promoter double mutation (p=0.005).



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