Abstract: Furthermore,
P203Q and
P203Q+
S210R increased the percentage of cells in
S-phase compared to wt, indicating cell-cycle progression (
P203Q:26+-13%;
P203Q+
S210R:29+-14%; wt:18%+-9, P <0.01.
Abstract: In in-vitro experiments,
P203Q,
S210R and
P203Q+
S210R significantly reduced the ratio [secreted/intracellular
HBsAg] compared to wt at each time-point analysed (P