HBV mutation literature information.


  Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA.
 PMID: 27650283       2017       Journal of hepatology
Result: revealed previously identified immune escape mutations within the 'a' determinant region (sS117T, sK122R, sI126N/S/T, and sG145R), carboxyl terminal truncation mutations (sC69* and sW182*) and additional rarely described mutations (sE2G, sL21S, sR24K, sT47K/A


  Characterization of hepatitis B virus (HBV) preS/S gene mutations in blood donors with occult HBV infection in the Baoji area of North China.
 PMID: 28236303       2017       Transfusion
Abstract: Specifically, the incidence of five OBI-related major hydrophilic region mutations (sS117T, sT118K, sT131N, sT134Y/L, and sD144E) was significantly higher in blood donors with OBI than in controls.


  Genotyping and Mutation Pattern in the Overlapping MHR Region of HBV Isolates in Southern Khorasan, Eastern Iran.
 PMID: 27882062       2016       Hepatitis monthly
Discussion: The Q129H was the most frequently detected escape mutant in this study (34.42%), followed by P127L/T (3.27%) and E164D, S117G/T, D144E, T125M, S143L, 1.63% for each; and their roles in the vaccine escape, Ig response and/or detection have already been established.


  Hepatitis B surface antigen variants in voluntary blood donors in Nanjing, China.
 PMID: 22500577       2012       Virology journal
Result: D99N, Q101R/H, L109I, I110N, T115S, S117T, P120S, K122R, S126T/A, P127H, A128V, Q129R/H/L, G130E, T131N/A, M133T/L/S, F134R/I/L, T143M, A159V, F161Y, W163G, E164G, V168A



Browser Board

 Co-occurred Entities




   Filtrator